MrTopStep Chart of the Day By NinjaTrader; $USDCAD $USDMXN ...

[unable to retrieve full-text content]Chart: Chart Analysis: With the U.S. election only one day away, how will you look to invest in the markets? Over the past few weeks, traders and investors have been bombarded with if/then market strategies based on which ...

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Sunday's local roundup: CNU field hockey wins 14th straight game, awaits NCAA fate

9:26 p.m. EST, November 4, 2012

Colleges
Field hockey: Lindsay Hendricks scored the game-winner with three minutes remaining in overtime to lead Christopher Newport, 8th in Division III, to a 2-1 win over Wilson in its regular-season finale. It was the 14th straight win for the Captains (16-1). Wilson took a 1-0 lead 4:45 into the contest, but a Belle Tunstall goal off an assist from Allie Hackbarth tied the game late in the second half.

CNU, 4-0 in overtime games on the season, registered its second straight OT victory. Friday, the Captains beat Houghton 2-1 in double OT.

CNU awaits word on who and where it will play in the NCAA Division III tournament. The first round begins Wednesday.

More field hockey: Top-seeded Drexel won its first CAA championship after beating second-seeded Northeastern 2-1 in overtime.

Christina Conrad scored the game-winner three minutes into the extra session, giving the Dragons (15-6) an automatic berth in the NCAA Division I tournament, which begins next weekend.

Women?s soccer: Eighth-ranked Virginia beat No. 7 Maryland 4-0 to win the ACC championship in Cary, N.C and gain an automatic berth in the NCAA tournament. The Cavaliers (16-4-1) won their second conference championship, matching the 2004 squad?s accomplishment.

The field of 64 will be announced Monday afternoon and first round action begins Friday. ...

Hofstra beat UNC Wilmington 2-1 in double overtime to win the CAA championship in Williamsburg.

Men?s soccer: Roanoke beat Virginia Wesleyan 1-0 in double-overtime to win the ODAC championship in Salem.

Women?s basketball: ODU sophomore Shea Kelley had 18 points and nine rebounds to lead Old Dominion past Elizabeth City State 70-50 in an exhibition game at the Constant Center. ...

William and Mary?s exhibition against Davis & Elkins was canceled due to travel disruptions in the Elkins, W.Va., region caused by Hurricane Sandy.

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Source: http://www.dailypress.com/sports/dp-sundays-local-roundup-cnu-field-hockey-wins-14th-straight-game-awaits-ncaa-fate-20121104,0,3159751.story?track=rss

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Wills Recreation and Sports Centre Tender ? News ? Tennis NSW ...

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Source: http://rosscletus.typepad.com/blog/2012/11/wills-recreation-and-sports-centre-tender-news-tennis-nsw.html

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The future of bike tires could be airless

15 hrs.

Devin Coldewey , NBC News

Airless tires have been proposed and demonstrated for cars many times, but one company is showing off a sophisticated new version intended for bicycles. Is this the end for bike pumps, or are the company's claims overinflated?

Britek Tire and Rubber has been working on an airless car tire for years that it calls the Energy Return Wheel. A rubber tread and sidewall is stretched over an internal scaffolding of rods and cushions that allows the tire to give ? and, the company claims, lose less energy to bumps and other compressions.

The bike tire uses the same concept, but naturally has?a lighter frame.?The rims are carbon fiber, with the rubber stretched tight around the outside.

Adjustments can be made to let the tires run harder or softer, and while the model in the video has an open frame, sidewalls could be added to prevent detritus from building up inside the tire.

There are airless tires already, which use a foam to fill where air would normally be, but there are shortcomings that have prevented widespread adoption. Durability and cost are factors, though the benefit of not having to worry about tire pressure or flats is considerable.

Cyclists will no doubt be skeptical, which is understandable, and until these high-tech tires are put to the test by real people in ordinary biking situations, it's a good idea to take their potential benefits with a grain of salt.

??via ChopMTB and Gizmag

Devin Coldewey is a contributing writer for NBC?News Digital. His personal website is?coldewey.cc.

Source: http://www.nbcnews.com/technology/futureoftech/future-bike-tires-could-be-airless-1C6791586

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Wilson Butler Designs $50M Expansion for Broward Center for the ...

Boston ? A phased $50 million expansion, renovation and rebranding of the Broward Center for the Performing Arts, designed by Wilson Butler Architects, will add new dining and hospitality venues, update existing theaters and significantly increase educational program space at the 20-year old Fort Lauderdale venue. The first phase includes a complete restoration of the Center?s flagship performance space, the 2,660-seat Au-Rene Theater that will feature new seating, a new orchestra pit, and new lighting and acoustical systems. When it reopened October 26th, the newly-upgraded Au-Rene Theater unveiled a Club Level seating area with exclusive access to a VIP lounge with full bar and food service and a dedicated center-view section on the Mezzanine Level.

Over the next 18 months, The Center?s expansion will include the new two-story Huizenga Pavilion, a sustainably-designed waterfront bistro offering casual dining in both indoor and outdoor settings, plus 3,000 square feet of event and conference space. Wilson Butler also designed the new three-story Rose Miniaci Arts Education Center, a 21st Century arts education wing with performance, studio and classroom space. Additional design components to be added include a new arrival plaza and marquee, the Intermezzo Tastings Room, a newly-restored lobby and front porch space a the Au-Rene Theater, outdoor seating in the Peck Courtyard and terraced dining areas on the hillside between the Center and the Riverwalk.

According to Scott Butler of Wilson Butler Architects, the central idea is to transform the audience experience by providing a range of venues and options that work together to encourage guests to arrive early and stay late. ?Most performing arts venues are only active for four hours per night for 200 nights a year. With this redesign and the addition of new dining and entertainment spaces, the Broward Center will be bustling for 14 hours per day, 7 days a week,? he said. ?There is already a strong community connection that people in South Florida have with Broward, and the new experiences available will extend that connection for future generations.

Another promising aspect of the guest experience enrichment is the Broward Center?s plans to take advantage of the expanded venues to bring the performers, artists and entertainment seen on stage to create pre-and-post-show activity to the new spaces.

?The opportunity is to create one-of-a-kind spaces and experiences that compete favorably with online entertainment, home theatre and other hospitality destinations,? said Scott Wilson. ?Performance and arts venues today need to change the conventional way of delivering entertainment in order to capture audiences that have many other choices available.?

The project is an encore assignment for firm co-founders Scott Butler and Scott Wilson. The two worked together on the design for the original Broward Center complex two decades ago as architects at Benjamin Thompson Associates. Scott Wilson was the Center?s original project architect and Scott Butler was its project designer. The project is being constructed by joint venture partnership Stiles/Miller LLC, and owner?s project manager Jacobs Engineering Group, Inc.

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Source: http://blog.high-profile.com/2012/11/01/wilson-butler-designs-50m-expansion-for-broward-center-for-the-performing-arts/

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Male fertility can be restored after cancer treatment, researchers find

ScienceDaily (Nov. 1, 2012) ? An injection of banked sperm-producing stem cells can restore fertility to male primates who become sterile due to cancer drug side effects, according to researchers at the University of Pittsburgh School of Medicine and Magee-Womens Research Institute. In their animal study, which was published today in Cell Stem Cell, previously frozen stem cells restored production of sperm that successfully fertilized eggs to produce early embryos.

Some cancer drugs work by destroying rapidly dividing cells. As it is not possible to discriminate between cancer cells and other rapidly dividing cells in the body, the precursor cells involved in making sperm can be inadvertently wiped out leaving the patient infertile, said senior investigator Kyle Orwig, Ph.D., associate professor, Department of Obstetrics, Gynecology and Reproductive Medicine, Pitt School of Medicine, and an investigator at Magee-Womens Research Institute.

"Men can bank sperm before they have cancer treatment if they hope to have biological children later in their lives," he said. "But that is not an option for young boys who haven't gone through puberty, can't provide a sperm sample, and are many years away from thinking about having babies."

Even very young boys, though, have spermatogonial stem cells in their testicular tissue that are poised to begin producing sperm during puberty. To see whether it was possible to restore fertility using these cells, Dr. Orwig and his team biopsied the testes of prepubertal and adult male macaque monkeys and cryopreserved the cells from the small samples. The monkeys were then treated with chemotherapy agents known to impair fertility.

A few months after chemotherapy treatment, the team re-introduced each monkey's own spermatogonial stem cells back in to his testes using an ultrasound-guided technique. Sperm production was established from transplanted cells in nine out of 12 adult animals and three out of five prepubertal animals after they reached maturity. In another test, spermatogonial stem cells from other unrelated monkeys were transplanted into infertile animals, which created sperm with the DNA fingerprint of the donor to allow easy tracking of their origin. In lab tests, sperm from transplant recipients successfully fertilized 81 eggs, leading to embryos that developed to the morula and blastocyst stages, which are the stages that normally precede implantion in the mother's uterus. Donor parentage was confirmed in seven of the embryos.

"This study demonstrates that spermatogonial stem cells from higher primates can be frozen and thawed without losing their activity, and that they can be transplanted to produce functional sperm that are able to fertilize eggs and give rise to early embryos," Dr. Orwig said.

The findings are encouraging because several centers in the U.S. and abroad already are banking testicular tissue for boys in anticipation that new stem cell-based therapies will be available in the future to help them achieve pregnancy and have their own biological children.

"These patients and their families are the pioneers that inspire our research and help drive the development of new medical breakthroughs," Dr. Orwig said. He directs the Fertility Preservation Program in Pittsburgh, a unique collaboration between Magee-Womens Research Institute, Magee-Womens Hospital of UPMC, Children's Hospital of Pittsburgh of UPMC, and the University of Pittsburgh Cancer Institute that offers education and treatment options for children as well as adult men and women who are at risk of becoming infertile due to medical problems including cancer.

"Many questions remain to be answered," Dr. Orwig noted. "Should we re-introduce the spermatogonial cells as soon as treatment is over, or wait until the patient is considered cured of his disease, or when he is ready to start a family? How do we eliminate the risk of cancer recurrence if we give back untreated cells that might include cancer cells? These are issues we still must work through, but this study does show us the concept is feasible."

Co-authors of the paper include lead author Brian P. Hermann, Ph.D., David K. Cooper, M.D., Ph.D., Angus W. Thomson, Ph.D., D. Sc., Gerald P. Schatten, Ph.D., and others from the University of Pittsburgh School of Medicine, as well as collaborators from the Oregon National Primate Research Center, University of California at Davis, ITxM Diagnostics in Pittsburgh, and CaridianBCT.

The project was funded by Magee-Womens Research Institute and Foundation, The Richard King Mellon Foundation, and National Institutes of Health Eunice Kennedy Shriver National Institute of Child Health and Human Development grants: R01 HD055475, R21 HD061289, U54 HD008610, P01 HD047675 and K99/R00 HD062687.

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Story Source:

The above story is reprinted from materials provided by University of Pittsburgh Schools of the Health Sciences.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

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Journal Reference:

1. Brian P. Hermann, Meena Sukhwani, Felicity Winkler, Julia N. Pascarella, Karen A. Peters, Yi Sheng, Hanna Valli, Mario Rodriguez, Mohamed Ezzelarab, Gina Dargo, Kim Peterson, Keith Masterson, Cathy Ramsey, Thea Ward, Maura Lienesch, Angie Volk, David K. Cooper, Angus W. Thomson, Joseph E. Kiss, Maria Cecilia T. Penedo, Gerald P. Schatten, Shoukhrat Mitalipov, Kyle E. Orwig. Spermatogonial Stem Cell Transplantation into Rhesus Testes Regenerates Spermatogenesis Producing Functional Sperm. Cell Stem Cell, 2012; 11 (5): 715-726 DOI: 10.1016/j.stem.2012.07.017

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/genes/~3/1fyp7hZC2gk/121101121538.htm

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